California Ag Network

Tag: National Institute of Food and Agriculture

  • USDA NIFA Launches Grants Opportunity to Combat Emerging Ag Threats

    The U.S. Department of Agriculture’s National Institute of Food and Agriculture (NIFA) announces the launch of a new competitive grants program aimed at rapidly addressing emerging and re-emerging pest and disease threats across the nation’s food and agricultural systems.

    The grants program, Rapid Response to Emerging and Re-emerging Pest and Disease Events Across Food and Agricultural Systems, is designed to deploy timely, science-based solutions to protect agricultural productivity, ecosystem health, and food security.

    “Invasive and emerging pests and diseases can devastate crops, livestock, and ecosystems, disrupt supply chains and threaten food security,” said NIFA Director Dr. Jaye Hamby. “This program empowers researchers and Extension professionals to act quickly, delivering practical solutions that safeguard our agricultural communities and the nation’s food supply.”

    This program is part of NIFA’s Agriculture and Food Research Initiative (AFRI), designed to improve plant and animal production and sustainability, and human and environmental health. AFRI is the nation’s leading and largest competitive grants program for agricultural sciences. These grants are available to eligible colleges, universities, and other research organizations.   

    With a maximum award of $500,000 and a grant duration of 12 to 24 months, the program supports grants for research, Extension, or integrated projects. Applications are accepted on a continuous basis, within 180 days of a qualifying pest or disease event, ensuring swift mobilization of resources when threats arise.

    Applications must directly address the effects associated with the emergence or re-emergence within the last 180 days of pests and/or disease in animal and/or plant production systems or within the food supply, and one or more of the following emphasis areas: One Health, plant and animal health, and ecosystem health.

    Funded projects will focus on applied research and Extension and outreach activities that generate actionable knowledge and tools. These may include:

    • Rapid understanding of pest/pathogen ecology, epidemiology, and immunology.
    • Development and validation of diagnostics, vaccines, and control methods.
    • Communication strategies, training programs, and best practices for mitigation.
    • Technologies and protocols for detection, management, and prevention.

    To ensure impact, projects must implement or develop at least one deliverable within six months of award receipt, with all activities completed within the grant period. Proposals are encouraged to integrate biological and social sciences, engage public-private partnerships, and support small- and medium-sized farms and ranches.

    “This program reflects USDA’s commitment to proactive, science-driven responses to agricultural threats,” Hamby said. “By supporting rapid innovation and collaboration, we’re helping communities stay resilient in the face of evolving challenges.”

    The program also welcomes proposals that address ecosystem health, including strategies to mitigate the environmental impacts of pests and diseases affecting plants, animals, and pollinators. Projects that incorporate community development, youth development, and 4-H are also eligible, provided they align with the program’s emphasis areas.

    Applicants are encouraged to coordinate efforts across institutions and regions, and to contact program staff at afri-rapidresponse@usda.gov with questions regarding project fit. While this program is designed for short-term, rapid response efforts, longer-term projects may be better suited for other AFRI program area priorities such as Agricultural Biosecurity, Diseases of Agricultural Animals, or Food Safety and Defense.

    For more information, visit nifa.usda.gov or email afri-rapidresponse@usda.gov. — By the USDA National Institute of Food and Agriculture

  • UC Davis Seeks Mighty Bacteria-Resistant Lettuce

    Maeli Melotto and her team at the UC Davis Department of Plant Sciences are looking for strains of lettuce that are genetically stronger at resisting bacteria that can make people sick. Their work has led to the identification of a gene that could play a role in the plant’s susceptibility to E. coli, a bacterium that causes potentially lethal intestinal illness.

    If the team could develop lettuce that can fight off the bacterium, that would avoid thousands of cases of sickness each year, cut production costs for farmers and save millions of dollars in public health expenses.

    Lettuce “sweats” substances onto the surface of leaves that E. coli and other bacteria can eat. In addition, bacteria can live just below the surface of lettuce leaves. Melotto, a professor specializing in the interactions between plants and microbes, is studying the genetic factors that determine how long bacteria can endure in the leaves. She and her team looked at more than 300 samples of lettuce and how they react to the pathogens, identifying the gene responsible for letting them in.

    Their next step is to test whether removing that gene could make lettuce more resistant to bacteria.

    Maeli Melotto, a professor in the UC Davis Department of Plant Sciences, and her team have found a gene she thinks governs whether lettuce can resist bacteria such as E. coli. (Trina Kleist/UC Davis)

    Some lettuce more likely to “feed” bacteria

    In a related study, Melotto’s team is looking at the surface of lettuce leaves and the layer just below the surface, which has tiny spaces where bacteria can live. The researchers want to learn what natural chemicals are in these two areas, and what compounds lettuce releases onto the surface of leaves that bacteria can use as food. Melotto expects to find that some types of lettuce are genetically disposed toward “feeding” bacteria.

    Melotto presented her findings at meetings earlier this year of the California Specialty Crops Council and the California Leafy Greens Research Board. Her work is funded in part by a five-year grant from the National Institute of Food and Agriculture.

  • Virginia Tech Researchers Developing New Vaccine for a Swine Coronavirus

    To address climbing economic losses from swine that contract the porcine epidemic diarrhea virus, Virginia Tech researchers in the College of Agriculture and Life Sciences and Virginia-Maryland College of Veterinary Medicine are developing a vaccine to combat the disease that has a near 100 percent mortality rate in newborn piglets.

    The disease emerged in the United States in 2013 and has since caused around $600 million in annual losses to swine producers. When combined with increased food prices for consumers and decreased exports of hogs, the associated loss amounts to more than $900 million annually in the U.S.

    While there are two commercially available vaccines for the virus commonly known as PEDv, neither are effective in preventing the disease. Mike Zhang, the principal investigator of the project and a professor in the Department of Biological Systems Engineering and Turner Faculty Fellow, saw the urgency for an effective vaccine against this virus.

    With a four-year, $630,000 grant from the USDA National Institute of Food and Agriculture, Zhang and co-principal investigator X.J. Meng, a University Distinguished Professor of molecular virology in the Virginia-Maryland College of Veterinary Medicine, are researching a nanoparticle-based vaccine to curb this highly contagious coronavirus among swine.

    Because of PEDv being in the coronavirus family, the researchers hope to gain knowledge and insight in order to swiftly produce vaccines against human coronaviruses and their variants.

    “This project will give us the opportunity not only to development a vaccine for swine, but gain insight into coronaviruses,” Zhang said. “While the viruses are different from each other, they share a lot of similarities. A lot of things that we learn from this project can be used to develop vaccines against human coronaviruses in the future.”

    Meng, also a professor of internal medicine at the Virginia Tech Carilion School of Medicine, the director of the Center for Emerging, Zoonotic, and Arthropod-borne Pathogens, and the interim director of the Fralin Life Sciences Institute, lent his help with his renowned knowledge as a virologist.

    “PEDv is one of the most devastating illnesses in the swine industry,” Zhang said. “Right now, we don’t have a good mitigation method. We want a safe and reliable tool in the arsenal of those in industry and our research will lead to that.”

    Over the last few years, vaccine development has targeted a safer, more effective way to deliver an immune response. So far, that target has landed on nanoparticle-based vaccines, to safely deliver a strong immune response in hosts to protect against disease.

    With the combination of nanotechnology and immunology work, the researchers targeted this delivery platform to develop nanoparticles displaying viral proteins as a vaccine candidate. The nanoparticle allows the researchers to put molecular adjuvant inside the particle, allowing it to become more potent.

    “Once you decorate the nanoparticle with viral proteins, the nanoparticle looks like a virus particle,” Zhang said. “Once you give that to the animal, it can have a very strong immune response toward the viral proteins on the nanoparticle to protect the vaccinated animals from the invading virus.”

    This platform has been used for other vaccines, and the researchers thought that because of its success elsewhere, it would be a good candidate for their PEDv vaccine.

    With the nanoparticle platform, the immune response can last quite a long time once injected into the subject. The initial shot could last as long as six months with a booster needed to complete the vaccine series – a common practice among vaccines of varying delivery platforms.

    “If we formulate the nanoparticle well, the immunity the vaccine can provide protection for is around half a year,” Zhang said. “But we have not tested beyond that duration using the nanoparticle delivery platform. It’s an extremely important subject to tackle.

    “This is a good duration to target,” Zhang continued, “because a body really doesn’t need a lot of antibodies circulating to provide a good immune response.”

    With the continued support of the Center for Emerging, Zoonotic, and Arthropod-borne Pathogens, the Fralin Life Sciences Institute, and the College of Agriculture and Life Sciences, the researchers have cutting-edge technology to tackle current and future viruses in animals of all species. 

    This project is supported by the USDA National Institute of Food and Agriculture, AFRI project (#2021-08581).